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HEALTH TECH

Improving Healthcare with Technology Depends on Faster Adoption of Innovation

Lucienne Ide, Founder, Rimidi

By Lucienne M. Ide, MD, PhD, Founder at Rimidi

Improving Healthcare with Technology Depends on Faster Adoption of Innovation

When Electronic Medical Records (EMRs) were introduced in the early 1970s the vision was clear: digitizing patient records would make healthcare more efficient, and better for the patient and provider. Fast forward to today—we’ve come a long way towards the goal of a better system, but we aren’t quite there. We’ve identified the industry’s pain points, and laid the groundwork for solutions. Widespread adoption of the three healthcare tech ideas below will be crucial to building a healthcare system that is better for patients and the clinicians alike.

Interoperability and SMART on FHIR

In 2018, the Centers for Medicare and Medicaid (CMS) renamed “Meaningful Use” to “Promoting Interoperability”, which is a good indicator that we are inching closer to greater efficiency in healthcare. Essentially, interoperability means the ability for health information systems and software apps to communicate, exchange data and use the data they’ve shared. “Digitizing healthcare” was initially driven by revenue optimization and then care standardization. Clinical efficiency seems to be the forgotten promise but will ultimately be one of the most meaningful outcomes. While EMRs have made huge strides in digitizing healthcare and allowing for data to lead the way, they haven’t always communicated well with each other or other technology. Enter Fast Healthcare Interoperability Resources, or ‘FHIR.’

FHIR is a standardized API that enables better discreet data exchange between different EHRs and health IT apps. FHIR created a shared language for health IT systems that all health IT players could use to exchange, interpret and process health data.

Substitutable Medical Applications and Reusable Technologies (SMART) added an additional layer of consideration to FHIR, addressing how users would engage with third-party applications inside of the Electronic Health Record (EHR), or other health IT platform workflow. The standard supports both single sign-on to third party applications as well as an integrated user experience. While it’s certainly still in its early days, SMART on FHIR is catching on across the industry.

Clinical Decision Support – CDS Hooks

The primary care physician checklist is ever-growing. Does the patient use tobacco? Do they wear a seatbelt? Do they floss? Do they eat enough kale? Instead of leveraging technology to empower the physician to know what is best for their patients, we’re adding more mandatory boxes to check that may not even pertain to that patient’s problem that they are presenting with. On top of that, physicians are tasked with keeping up with rapidly changing clinical guidelines and new therapeutics. Arming clinicians with the information they need to make the best decisions for their patients—while working within their workflow–is essential.

What if the software systems that clinicians use could be more dynamic? What if technology could prompt the clinician with the information they need when they need it in order to make a more personalized clinical decision? The CDS Hooks specification was created to support this idea. The vision for CDS Hooks is this: A ‘hook’ is programmed within the clinician’s workflow in the EHR, and can share information with third party applications, like the SMART on FHIR apps mentioned above. The app can then trigger a CDS, or Clinical Decision Support, notification and prompt the clinician with relevant information. For example, a new lab result may be available in the EHR indicating worsening kidney function. When the clinician opens that patient record, the EHR silently communicates with the third-party SMART on FHIR app, or launches the app automatically, to show guideline-based medication dosing recommendations for patients with compromised kidney functionPut simply, embedded clinical decision support tools will make it easy for physicians to do the right thing for their patient, and hard to do the wrong thing.

Remote Patient Monitoring and Personalized Medicine

The vison of ‘personalized medicine’ is entirely dependent on bringing in patient-generated health data from connected devices (think step counters with apps but measuring more clinical information, like blood pressure or blood-glucose levels). Clinicians need a way to know what’s going on with patients the 8,516 hours per year that they aren’t engaging with the healthcare system, versus the four hours they may be with their doctor. This data set has been largely ignored but as price points come down on cellular and Bluetooth-enabled devices, data transmission, and cloud storage, connected devices are finally be available to the masses. Interoperability allows us to pull this data into analytics platforms and connect it with patient record data from the EHR, giving clinicians a more complete view of their patients’ health—whether at the point-of-care or virtually.

Not only can technology like this arm clinicians with a better view of each patient’s unique needs, but it can enable remote monitoring to detect costly complications before they happen, and prompt clinicians to intervene with appropriate guideline-based management.

Make no mistake: The convergence of these three emerging healthcare technology trends can change healthcare—but providers must be ready to adopt them.

After working as a physicist, a venture capitalist, an academic clinician and scientist, Lucienne Ide, MD, PhD, decided to start Rimidi to drive innovations in the healthcare industry.

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HEALTH TECH

The Future of Healthcare Lies in Decentralization

By: Pradeep Goel, Chief Executive Officer of Solve.Care

The Future of Healthcare Lies in Decentralization

The healthcare sector is one of the fastest growing industries worldwide and as such insurmountable efforts have been expended to adapt to the constant advances in technology and the needs of patient care. One of these advances that is quickly becoming the go to for new healthcare systems and solutions is blockchain. Blockchain technology has been helping to lead in the decentralization of almost every industry today. For the healthcare in particular, it can greatly streamline the administration, relationships and interactions among stakeholders, and management of logistics that health systems are built on and the overall quality of care they can provide.

The main aim of utilizing blockchain technology and decentralizing healthcare is to address the issues and problems affecting the industry. By putting patients at the center of their own healthcare journey, decentralizing the healthcare sector with the help of blockchain helps provide patients with the information, ownership, and control over their own healthcare data. This is achieved by decentralizing data into individual patient nodes. This is also useful in population health management as patients can easily provide consent for access to their health data to be shared for the creation of a shared archive of health information of any specific condition. It also allows the patient the ability to easily monetize parts of healthcare data. All this can be done anonymously, thus protecting their privacy.

It is well known that different healthcare organizations often keep fragmented records for patients, particularly when more than one organization is involved in the care. Blockchain can be used to help to eliminate this issue and ensure that there are no missing or fragmented records by creating a distributed electronic health record (EHR) ecosystem made up of individual patient nodes, where they have their complete health records. This will further help to ensure improved quality, eliminate repeated and expensive tests, reduce errors, which will provide financial and operational benefits to healthcare organizations.

Other than the aforementioned advantages of a decentralized healthcare sector with an increased concentration on the patient, the approach can be used to improve healthcare on a global scale. Blockchain frameworks will help support and strengthen disease surveillance systems in the case of outbreaks, organize research on a global scale, and even provide a consensus to what is the best method to combat specific diseases.

Blockchain technology is also immutable and traceable. This allows the user to pinpoint specific transactions or actions that have been taken, whether it be in the patient journey or when it comes to logistics of pharmaceuticals. It is the best way to minimize or even eliminate healthcare and pharmaceutical fraud and errors. Overall, blockchain and a decentralized healthcare sector is the next logical step towards a more efficient, patient focused, and better healthcare system.

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HEALTH TECH

AI to help kids struggling with ADHD, Autism, Asperger Syndrome , PDD-NOS & other ASD’s

Stephane Bourles, CIO, Brain Balance

By Stephane Bourles, CIO at Brain Balance

AI to help kids struggling with ADHD, Autism, Asperger Syndrome (ASD), PDD-NOS and other ASD’s

Left Brain or Right Brain?

In a properly functioning brain, both hemispheres communicate equally and at lightning speed, millions of times per minute. In a poorly functioning brain, the left and right sides of the brain only impart partial information, causing frequent miscommunication. This is called Functional Disconnection and is the root of many types of learning, behavioral and social problems found in children. The Brain Balance program puts the left and right brains back in sync using sensory motor exercises, academic skill building, and nutrition guidelines.

How does the Assessment Work?

The assessment consists of sensory, motor, and academic testing of more than 900 functions. The outcome of this assessment is a highly customized report providing parents with a complete understanding of their child’s behavioral, social, and academic skill levels.

We use AI to determine which brain hemisphere we believe to be stronger or weaker. The Machine Learning algorithm used for the assessment is not always accurate, which we know based on the feedback from our staff—yes we let them disagree with the system, which is intended as a tool to help them support their own assessment, but not to necessarily force them into a decision they don’t agree with.
But as valuable as an individual observation based on years of experience is, it still remains just the view of one individual. That is why we look at Artificial Intelligence as a new solution combining neural network architectures with massive computing power to enable our solution to learn a pattern from large datasets and make statistical predictions based on test results and feedback we already have for tens of thousands of students.

What is next?

Thanks to many product releases with different Machine Learning models we tested, we were able to improve our assessment accuracy and achieve precision, recall and F1 scores over 0.95. The limitation of this AI model is it is not 100% accurate and you don’t know for sure the source of truth. Since AI is a “black box” which can’t explain its prediction for most models, you have to trust your staff first.

Similar to clinical decision support systems helping healthcare practitioners, we believe this fast growing dataset about children, combined with new Artificial Intelligence models such as Explainable AI, will help our staff improve a child’s initial assessment, which will then improve our overall program’s results.

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HEALTH TECH

Read Your DNA Story

Anne Wojcicki, Co-Founder & CEO, 23andMe
Anne

Read Your DNA Story

“After 19 years of not knowing anything, and then just from spitting in a tube, I have a pile of information all about me.” “I am so grateful for the opportunity to finally have confirmation of my history.” “I have never had anyone look like me…It’s just great to find out who I am.” Well, as thrilling and amazing as these testimonies sound, understanding and decoding DNAs is the most exciting scientific discovery of all time. People have spent decades together trying to track down their lost genetic ancestry or loved ones for many years. Thanks to the “secret code” in all of us! Individuals can today get easy and affordable access to their genetic information and this is made possible by 23andMe. With an aim to help people access, understand, and benefit from the human genome, they generate the data that not only reveals ancestry insights but also enables groundbreaking research and innovative products.

“For a little bit of spit and a few hundred dollars, we can check out genetic predictions for traits we already know we have—perhaps blonde hair or blue eyes—as well as susceptibilities for diseases we may have yet to develop, such as cancer or diabetes,” notes Anne Wojcicki, the pioneer woman renowned for bringing genome mapping to the common man for tracking linage as well as medical treatment. Through her company, Anne has built one of the world’s largest databases of individual genetic information. Its novel, web-based research approach allows for the rapid recruitment of participants to many genome-wide association studies at once, reducing the time and money needed to make new discoveries, and the company has created a proven and standardized resource for finding new genetic association and confirming genetic loci discovered by others. “In a world where health is poorly understood, we use data to better understand wellness and disease. We bring science to our customers and help them use it in meaningful ways.”

As Simple As Spitting

Primarily, the company offers two Personal Genetic Services: Health + Ancestry and Ancestry. Both services require submitting a saliva sample using 23andMe’s saliva collection kit that is then sent to the lab for analysis. The Health + Ancestry Service provides insights on one’s health predispositions, carrier status, traits, wellness, and ancestry. This is done through analyzing, compiling, and distilling the information extracted from one’s DNA into 125+ reports that customers can access online and share with family and friends. This Ancestry Service helps to understand who one is, where his/her DNA comes from and his/her family story. This DNA information is then entered into the reports of 23andMe services: Ancestry Composition, Ancestry Detail Reports, Maternal & Paternal Haplogroups, Neanderthal Ancestry, DNA Family, and DNA Relatives to retrieve results. Upon receiving the sample, the company’s CLIA-certified lab extracts DNA from cells in the saliva sample and processes the DNA on a genotyping chip that reads hundreds of thousands of locations in the genome. Eventually, the genetic data is analyzed, and personalized reports are generated based on well-established scientific and medical research.

Betty’s Birthday Wish

Betty Jeannotte’s only wish when she turned 100 was to learn about her ancestry. “Years and years ago, I’d done a little research, but I never got very far,” she said. “And I was curious.” She got a 23andMe kit and a chance to work with a genealogist to find out a little bit more about her ancestry. He found 7 generations of her maternal family. The information added another layer to what she already knew. Her 23andMe Ancestry Composition showed she’s about 80 percent English and Irish with a little bit of German in the mix. That reflects accurately with what she knows about her parents’ family histories. Her mom was “of Yankee stock,” while her dad, who had been a vaudeville magician, was a Bostonian whose family originally came from Ireland.

For 23andMe, the mission is about transforming lives. They are keen to provide more regions, more connections and more ways to help people like Betty know their DNA story. Some ancestry services are records-based, which means that the data can be retrieved from historical records such as birth, death and marriage certificates, to trace a lineage. 23andMe offers genetics-based ancestry reports and tools, which means that they analyze a DNA to trace one’s lineage and learn about his/her ancestral origin through 23andMe Ancestry Composition.

Trace. Discover. Connect

Furthermore, 23andMe’s unique service, Haplogroups provides reports on one’s maternal and paternal lineage by identifying their haplogroups. A haplogroup can trace part of his/her ancestry back to a specific group of individuals in the distant past. This helps in understanding how the migration of one’s DNA tells the story of their ancestors. Alongside, one can explore genetic similarities and differences between themselves and their relatives using Share and Compare service.

“We can even point to specific Neanderthal DNA that is associated with traits that you might have, like height and back hair,” points out Anne. Even though Neanderthals vanished about 40,000 years ago, their DNA lives on. Research tells us that they interbred with humans around 60,000 years ago. 23andMe can tell how much of one’s DNA is derived from Neanderthals and how that compares to others.  Moreover, 23andMe’s DNA Relative Finder helps in connecting with people who share DNA with you and message them. This enables them to meet relatives—maybe even hear new family stories, share photos and get a better understanding of their family’s’ history.

Making an Impact

Over the years, Anne’s determination and power has shocked the scientific world. As a part of her mission to change healthcare through empowering their consumers, her company also conducts its own research to try to identify new therapies for both common and rare diseases. “I am obsessed with bringing the consumer voice to healthcare.” To further this effort, 23andMe’s genetic research gives everyday people the opportunity to make a difference by participating in a new kind of research—online, from anywhere. Once participants answer online survey questions, researchers link their genetic data to study topics from ancestry, to traits, to disease. These contributions help drive scientific discoveries. On average, a customer who chooses to opt into research contributes to over 230 studies on topics that range from Parkinson’s disease to lupus to asthma and more. “With the help of our 23andMe community, we believe we can accelerate research and make an impact with our genetic data.” Alongside, all researches are governed by an Institutional Review Board (IRB). The IRB is an independent ethics panel that ensures all research is conducted in accordance with government and ethical guidelines.

For 23andMe, genetics is personal! This has in fact impacted many lives, over the years, by giving people a chance to “find family and answers”, “reveal ancestry”, “strengthen family bonds”, and “get a stronger sense of their self.” Anne calls this, “democratizing personal genetics and making it more accessible,” as she is considers each life story a pathway to connect to humanity and improve the world.

Anne

Company: 23andMe

Website: www.23andme.com

Management: Anne Wojcicki, Co-Founder & CEO

Founded Year: 2006

Headquarters: Mountain View, California

Description: Personal genomics and biotechnology company

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