Adaptiiv: Developing Personalized Healthcare Technology
Peter Hickey, CEO, Adaptiiv

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Developing Personalized Healthcare Technology

A 67-year-old female was treated at the Nova Scotia Health Authority for mycosis fungoides of the forehead, eyelid, and nose with mycosis fungoides involving the upper face. As a part of her treatment plan, the application of bolus for Modulated Electron Radiation Therapy (MERT) was necessary to deliver the prescribed dose to the skin surface to treat her disease with two separate electron fields. This is where Adaptiiv’s 3D printing software solution proved phenomenal in creating a highly conformal bolus for MERT for the superior field, allowing modulation of the electron fluence to spare distal structures (Figures 1 and 2).

The technology’s accuracy and high resolution made it best suited for MERT bolus and obtained 90 isodose to 92.5 percent of planning target volume (PTV). The treatment plan achieved relative sparing of all the organs at risk distal to the target volume. The 3D printed bolus was rigid and could be reproducibly placed at the times of planning a computed tomography and daily treatments, without causing discomfort (Figure 3).

As a medical software and 3D printing technology solution provider, Adaptiiv takes a personalized patient care approach while helping the healthcare industry optimize 3D printing technology software. “With our passion for innovation, we have developed a clinically viable software platform that allows cancer treatment centers to automatically fabricate and 3D print patient-specific accessories used in radiation therapy,” says Peter Hickey, co-founder and CEO of Adaptiiv.

Their software platform seamlessly integrates within existing radiation treatment processes/workflows, using proprietary algorithms to automatically design patient-specific accessories. This eliminates the need to correct anatomical irregularities and delivers precise and accurate radiation doses to the target area, protecting healthy tissue (organs-at-risk, OARs) surrounding the area. While it wholly revolutionizes how the radiation process is planned and completed, it also ensures precision and ease of use through automation, making Adaptiiv’s 3DBolus Software the best-in-class software solution currently available in the industry. “What used to take practitioners’ hours or days to fabricate complex devices, such as custom fit and modulated boluses or brachytherapy devices, now only takes minutes. Additionally, our software integrates directly into treatment center’s current workflows, allowing users to verify their plan using our newly designed object directly in their Treatment Planning System (TPS) prior to printing,” notes Hickey. In terms of the actual product, they provide an automated way to develop an accessory as prescribed by the doctor. “Our algorithms modulate the design of the accessory based on key information provided from the treatment planning system. This allows our clients to develop patient-specific designs that improve treatment delivery, decrease setup time, reduce costs, and improve the patient experience.”

As part of being the first company in the world to receive U.S. FDA 510(k) regulatory clearance to market 3D printing software for use in radiation oncology, Adaptiiv has tested, validated, and verified filament materials and has a fully validated 3D printer to use with their software. “We have tested printers that claim 100 percent infill only to find they are closer to 80 percent. This affects the accuracy of dose delivered to the patient,” says Hickey.  Adaptiiv software includes 3 modules—uniform thickness bolus, modulated electron bolus, and HDR surface brachytherapy—with features like in vivo dosimetry, cleaving, and a hotspot correction tool. “These were the first modules we offered because that was where we saw the most obvious demand. Today, we have as many as five more modules planned for this year, all of which will be done in conjunction with some of the most recognized centers in the world.”

Adaptiiv has gained customers in 7 different countries and has partnered with some truly exceptional distributors to provide them with global access. With a diverse team that includes physicists, radiation therapists, software engineers and developers, the company understands every aspect of a healthcare center, including the types of treatment delivered, specific workflows, and comfort levels with new technologies. “We are keen on listening to our customers to remove roadblocks and ensure our printing software fits seamlessly into users’ current practices, while providing a clear ROI to our customers,” concludes Hickey.

Company: Adaptiiv


Management: Peter Hickey, CEO

Founded Year: 2016

Headquarters: Halifax, Nova Scotia

Description: A medical software and 3D printing technology solution provider.

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